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The laboratory for neuroanalytics is led by Dr William McGeown, who is based within the School of Psychological Sciences and Health at The University of Strathclyde.  The lab primarily focuses on the analysis of neuropsychological assessment data, neuroimaging data (structural and functional magnetic resonance imaging data), and electrophysiological data (human electroencephalography).  Current projects include those involving primary data collection and analysis, in addition to secondary data analyses drawing upon initiatives such as the Alzheimer’s Disease Neuroimaging Initiative (ADNI).

NEUROPSYCHOLOGY

NEUROIMAGING

NEUROPHYSIOLOGY

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Key research themes:

  • Improving early and differential diagnosis of Alzheimer’s disease and other dementias

  • Understanding neuropsychiatric symptoms in neurodegenerative disease

  • Investigating the neurobiological bases of suggestibility

Available technologies:

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  • 128 channel EGI EEG system

  • 32 channel Biosemi EEG system

  • tDCS (Neuroconn)

  • Biopac system (can be configured for EEG, GSR, heart rate, etc.)

Projects/Collaborations:

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Investigating the neurobiological basis of suggestibility (hypnotic and waking).  This project running at the University of Strathclyde is funded by The Leverhulme Trust and the BIAL Foundation. It involves behavioural assessment, structural and functional magnetic resonance imaging, electroencephalography and genetic assessment.  Collaborators on the project include Prof Irving Kirsch (Beth Israel Deaconess Medical Center and Harvard Medical School, USA), Prof Giuliana Mazzoni (Sapienza University of Rome, Italy), Prof Annalena Venneri (University of Sheffield Medical School), Dr Niia Nikolova (The Embodied Computation Group, Aarhus University, Denmark), Iris Ionita and Dr Rothwelle Tate (University of Strathclyde [UoS]).

 

EEG and MRI biomarkers for Alzheimer’s disease. Collaborative partners include Cognision (USA-based industry partner), the Multimedia/Multimodal Signal Enhancement and Analysis Lab (MUSAE) lab (based within the Institut National de la Recherche Scientifique, University of Quebec, Canada).

 

Cognitive and electrophysiological biomarkers of Alzheimer’s disease.  Collaboration with Dr Mario Parra of the Applied Cognition Lab (UoS) and Kerry Kilborn (University of Glasgow [UoG]).

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Investigating the relationship between neurobiology, and cognitive and neuropsychiatric symptoms in neurodegenerative disease. Collaboration with Prof Annalena Venneri and Dr Matteo De Marco (University of Sheffield).

 

Developing blood-based biomarkers for dementia.  Doctoral student: Zanib Panni.  Collaborators include Dr Matthew Baker (ClinSpec Dx), Dr Terry Quinn (University of Glasgow), Dr Fabricio Oliveira, Eduardo Ferreira Castro-Neto, Sandro Luiz de Andrade Matas, Paulo Henrique Ferreira Bertolucci, Maria da Graça Naffah-Mazzacoratti (Universidade Federal de São Paulo [UNIFESP], Brazil).

 

Investigating the rehabilitative potential of mirror therapy and transcranial direct current stimulation. PhD student: Lesley-Anne Rollins - funded by the ESRC interdisciplinary studentship).  Collaborators include Prof Madeleine Grealy (1st supervisor), Prof Bernard Conway (University of Strathclyde), Dr Terry Quinn (University of Glasgow).

 

Investigation of treatment potential of an intense physiotherapy based intervention with motivational optimization (PhD student: Luke Meneilly - internal University PhD studentship). Collaborators include Prof Madeleine Grealy (1st supervisor)(UoS) and Dr Terry Quinn (University of Glasgow).

 

Investigating cortical activity relating to judgements about relevance (information retrieval).  PhD student: Zuzana Pinkosova - funded by the EPSRC. Collaboration with Dr Yashar Moshfeghi (1st supervisor and Director of Laboratory IX).

 

Investigating the effects of intergenerational engagement.  PhD student: Anna Krzeczkowska (internal University PhD studentship). Collaboration with Louise Brown Nicholls (1st supervisor)(UoS) and Prof Alan Gow (Heriot-Watt University).

 

Cognitive training in older adults.  Collaboration with Dr Kristin Flegal (Scientific Lead for the Scottish Imaging Network: A Platform for Scientific Excellence [SINAPSE]).  Funded by the Neurosciences Foundation.  Additional collaborator: Dr Louise Brown Nicholls (UoS).

Funding gratefully acknowledged from:

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  • The Leverhulme Trust

  • The BIAL Foundation

  • ESRC

  • EPSRC

  • ARUK

  • Neuroscience Foundation

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